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Alcohol Misuse and Kidney Injury: Epidemiological Evidence and Potential Mechanisms PMC

There is a direct relationship between blood pressure and kidneys’ function. Experts say that having 4 to 7 drinks a day is the cause of this disorder. Acute pancreatitis related to alcohol intake changes the level of phosphorus in the blood. This increases the amount of fluid reabsorbed by the kidneys, raises potassium levels, and lowers sodium levels. Low potassium can cause low sodium levels and increase the risk of hyponatremia (low sodium in the blood). Too much of this drink prevents the kidneys from retaining any water.

  • In summary, there is no exact evidence that alcohol consumption aggravates the state of CKD or increases all-cause mortality in CKD, and the protective effect of abstinence on such patients is unclear.
  • In contrast, Menon et al. could not find any adverse or beneficial effects of alcohol consumption on kidney function in the elderly [88].
  • This finding suggests that rhabdomyolysis and myoglobin toxicity may trigger oxidative stress in the kidney via mitochondrial injury.
  • For these reasons, it’s natural that when your kidneys have to work extra hard to rid the body of excess alcohol, you may experience pain.

This is because liquor selectively increases renal perfusion and basal metabolic rates of renal tubes hence causing an increase in diuresis, leading to massive dehydration. Dehydrated kidneys are unable to function properly, and the subsequent consumption of the next portion of ethanol makes this situation even worse, which eventually leads to the malfunction of the organ. According to the National Kidney Foundation, regular heavy drinking can double the risk of getting chronic kidney disease (CKD). One study found that light drinking did not elevate blood pressure. Alternatively, moderate and heavy drinking had a 79 and 91% increase in blood pressure.

Alcohol and Chronic Kidney Disease

In addition, excess fluid accumulates in spaces between cells, clinically manifested as swelling (i.e., edema) of the lower back and legs. As long as cirrhotic patients remain unable to excrete sodium, they will continue to retain the sodium they consume in their diet. Consequently, they will develop increasing ascites and edema and experience weight gain. In some cases, vast amounts of abdominal fluid may collect, occasionally more than 7 gallons (Epstein 1996).

Alcoholic drinks, especially beer, are usually rich in carbohydrates, which can raise blood sugar levels, leading to type 2 diabetes. The intoxicant increases the risks of developing type 2 diabetes by excessive amounts of calories and carbohydrates. Liquor can also lead to type 2 diabetes by stimulating appetite, leading one to eat more than normal. Interested in learning how that sip of alcohol affects the kidneys? Keep reading to find out more about the effects of alcohol on kidney health. The intoxicant not only affects the cognitive function of the body but also damages the vital organ.

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Men generally drink more than women, and men have higher rates of alcoholism than women. Furthermore, the cardiovascular-protective effects of estrogen [91,93] should not be overlooked. In many patients with liver cirrhosis, the kidneys’ ability to create dilute urine is compromised, leading to a state of abnormally https://ecosoberhouse.com/ low sodium concentration (i.e., hyponatremia). In hyponatremic patients, the amount of fluid retained by the kidneys is disproportionately greater than the amount of sodium retained. In other words, the kidneys’ ability to excrete excess fluid by way of dilute urine is impaired, and too much fluid is reabsorbed.

There are treatments available — diet and exercise changes, birth control pills and the diabetes drug metformin — but they don’t work for everyone. Anecdotally, some people who take drugs like Ozempic say the alcohol and kidneys medications make them want to drink less, and in some cases, turn them off alcohol altogether. Because people feel full when they take these medications, they may lose interest in alcohol as well as in food.

How to Drink Safely

Furthermore, alcohol has an anti-inflammatory effect, with increased serum interleukin-10 levels and decreased serum interleukin-16 levels [20]. Alcohol consumption can raise high-density lipoprotein cholesterol concentration [21,22], improve insulin sensitivity [23], and reduce platelet aggregation rate and fibrinolysis [21,22]. Alcohol consumption, including vodka and red wine, also reduced serum insulin concentrations and enhanced the insulin sensitivity index [24,25]. A moderate amount of alcohol drinking decreases the risk of developing diabetes, showing a U-shaped association [26]. Even without binge drinking, regularly drinking too much too often can also damage the kidneys.

alcohol and kidneys

According to Dr. Bobart, there’s no research to suggest a link between alcohol and kidney pain. The CDC recommends limiting alcohol to one drink a day for women and two for men. Since edibles aren’t federally regulated, they’re more like the Wild West. Many over-the-counter and prescription medications can have adverse health consequences whenmixed with alcohol. These medications include many popular painkillers such as acetaminophen (Tylenol); sedative drugs such as diazepam (Valium); and cough, cold, and allergy remedies.

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